Fascination About Wockhardt Promethazine with Codeine
Fascination About Wockhardt Promethazine with Codeine
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Just take this medication by mouth with or without food stuff as directed by your medical doctor, ordinarily each and every four to 6 several hours as necessary. This medication is often taken with foodstuff if abdomen upset takes place. Consume an abundance of fluids any time you use this medication Except usually directed by your medical doctor.
Fetal/Neonatal Adverse Reactions Extended usage of opioid analgesics all through pregnancy for medical or nonmedical applications may end up in physical dependence from the neonate and neonatal opioid withdrawal syndrome shortly immediately after beginning.
It truly is not known if this medication passes into breast milk. Nevertheless, it could have unwanted outcomes over a nursing toddler. Speak to your health practitioner prior to breastfeeding.
Postmarketing instances of respiratory despair, like fatalities happen to be reported with use of promethazine in pediatric patients.
A most likely deadly symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) continues to be documented in association with promethazine HCl alone or in combination with antipsychotic medicine.
This may be related with a lessen in efficacy, and in a few patients, may perhaps result in symptoms and signs of opioid withdrawal.
Promethazine has an elimination 50 percent-life of 10-fourteen hrs, with excretion of metabolites appearing while in the urine and feces. The sulfoxides of promethazine and N-demethylpromethazine are definitely the predominant metabolites appearing from the urine.
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This medication may well have sugar and/or alcohol. Caution is recommended When you've got diabetes, alcohol dependence, or liver illness. Question your medical doctor or pharmacist about applying this product safely and securely.
Because of the possible for promethazine to reverse epinephrine’s vasopressor influence, epinephrine shouldn't be utilised to deal with hypotension involved with promethazine overdose.
Promethazine with Codeine Oral Solution is contraindicated for all kids more youthful than twelve decades of age [see Contraindications ( four) ]. Promethazine with Codeine Oral Solution is contraindicated for publish-operative administration in pediatric clients young than 18 a long time of age subsequent tonsillectomy and/or adenoidectomy [see Contraindications ( four) ]. Stay clear of the use of Promethazine with Codeine Oral Solution in adolescents twelve to eighteen many years of age who have other possibility components which will improve their sensitivity for the respiratory depressant results of codeine Until the advantages outweigh the challenges.
Don't get any benzodiazepines or medicines that can result in drowsiness or sleepiness all through cure with PROMETHAZINE WITH CODEINE ORAL SOLUTION. Check with your Health care service provider for an index of these medicines if You're not positive.
Promethazine hydrochloride was not mutagenic inside the in vitro bacterial reverse mutation assay or clastogenic within the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay.
Location the combination in a very container such as a sealed plastic bag and toss it absent inside the home trash. You may also follow your point out or regional recommendations regarding how to securely throw away PROMETHAZINE WITH CODEINE ORAL SOLUTION.